BONE MARROW TRANSPLANT
Bone marrow in our bones is responsible for formation of blood cells. In fact, all the blood cells are formed by a subset of bone marrow cells known as “hematopoietic stem cells” or simple “stem cells”. These blood cells have special characteristics i.e. they can renew themselves, and have the capability to develop into any type of blood cells. Nowadays, hematopoietic stem cells can also be obtained from peripheral blood after treatment with certain growth factors or from umbilical cord. Thus, “Hematopoietic stem cell transplantation” is now preferred to “Bone marrow transplantation”, wherein the stem cells from bone marrow that produce red blood cells, white blood cells, and platelets are injected into a recipient after a short course of chemotherapy called conditioning. Today, this is a viable option for several disorders and with a continued research, success has remarkably improved.

Why Choose Us

  • Team of eight doctors including haematologists and haemato-oncologists.
  • Completed over 1200+ bone marrow transplants.
  • 22-bedded transplant unit
  • One of the largest centres for multiple sclerosis, sickle cell and aplastic anaemia treatment
  • Global standard of infection control practises
  • One of the few centres performing matched unrelated donor transplant for thalassemia

Our Team of Experts

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Sat, 04/01/2023 - 16:22

FAQs

  • What is a Bone Marrow Transplant (BMT) ?
    A Bone Marrow Transplant, also known as a Hematopoietic Stem Cell Transplant (HSCT), is a medical procedure that involves replacing damaged or diseased bone marrow with healthy stem cells. These stem cells can come from the patient themselves (autologous transplant) or a compatible donor (allogeneic transplant).
  • What is the purpose of a Bone Marrow Transplant ?
    The primary goal of a Bone Marrow Transplant is to treat various conditions like certain types of cancer (leukemia, lymphoma, multiple myeloma), severe aplastic anemia, and genetic disorders that affect the production of blood cells.
  • How does a Bone Marrow Transplant work?
    The procedure involves three main stages: a. Conditioning: High-dose chemotherapy, radiation, or a combination of both is administered to destroy the diseased marrow and suppress the immune system to prevent rejection. b. Transplantation: Healthy stem cells are infused into the patient's bloodstream, where they migrate to the bone marrow and start producing new blood cells. c. Engraftment: It is the phase where the transplanted stem cells begin to grow and produce healthy blood cells.
  • What types of Bone Marrow Transplants are there?
    There are three main types of Bone Marrow Transplants: a. Autologous Transplant: The patient receives their previously collected and stored stem cells. b. Allogeneic Transplant: Stem cells come from a healthy donor whose tissue type closely matches the patient's. c. Syngeneic Transplant: The stem cells come from an identical twin of the patient.
  • How is a donor matched for an allogeneic transplant?
    Human leukocyte antigen (HLA) testing is performed to determine the compatibility between the patient and potential donors. The more closely the HLA markers match, the better the chance of a successful transplant.
Cancer Treatment At Fortis Hospital

With timely diagnosis,. of Cancer, timely diagnosis can save your life. Fortis Hospitals has taken multiple safety measures so you receive safe care for all your health needs. With cancer detection and treatment, acting at the right time may make all the difference. So, don’t let the pandemic delay your cancer treatments, Visit Fortis Hospital, your Guardian of Health for Comprehensive and safe oncology and oncosurgery procedures.
 

Right from the diagnosis to the staging of the disorder and its treatment and management, our doctors brainstorm together on the best mode of treatment following stringent diagnostic and staging protocols, making Fortis Hospital at the frontline of specialized hemato oncology care.

Immense research goes into determining the type and nature of the underlying disorders afflicting the blood. In the hands of the best medical experts at Fortis Hospital , patients can be assured of treatment excellence.


Hematology then is the study, diagnosis, prevention and treatment of blood diseases, while oncology is about cancers. Hemato-oncology is a combination of both these blood diseases that include iron deficiency anemia, hemophilia, thalassemia and sickle cell disease, as well blood cancers such as leukemia an lymphomas

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Why Choose Us

  • 24*7 well equipped Ambulance and Emergency Services
  • More than 37 year of clinical experience
  • International Patients Services
  • Highly Advanced Medical Care
  • 24*7 well equipped Ambulance and Emergency Services
  • JCI and NABH Certified Hospital(Fortis Hospitals)
  • Dedicated Block for Oncology OPD’s

Our Team of Experts

FORTIS HEALTHCARE?

FAQs

  • What is the cut-off age (eligibility) for a bone marrow transplant?
    Bone marrow cell donors and recipients of all ages who meet strict health criteria are eligible for bone marrow transplant. This means both, the donor and the patient who is to receive the donor bone marrow cells, will undergo stringent tests to check for underlying risks and heath issues that could restrict the treatment. While younger donors under the age of 65 years are preferred for BMT, transplant recipients age can be extended upto 75 years if they are otherwise fit and without accompanying severe illness.
  • Can leukemia be cured after bone marrow transplant?
    There are four common types of leukemia. Of these, Acute Leukemia is the highly curable form of adult leukemia. This is attributed to the advances in the diagnosis and high-precision treatment of this type of blood cancer. Cure rates of 80-90 percent following bone marrow transplant have been reported from centers specializing in acute leukemia treatment, including Fortis Hospital in Mumbai, India.
  • Which family members can donate bone marrow?
    Seeking a bone marrow donor within the family is the first option. A brother or sister is most likely to be a perfect match as a donor. This is called a matched sibling donor transplant. There’s a 1 in 4 chance of the bone marrow cells matching among siblings. One’s parents, own children, and other relatives can sometimes be good matches. Only about 30% of those who need a bone marrow transplant can find a matching donor in their own family.
  • Is bone marrow transplant painful?
    The transplant procedure is not painful because it is not surgery. In fact, it is similar to a blood transfusion. The bone marrow cells are infused into the vein directly through a thin catheter or intravenous tube. This process could take a couple of hours and the recipient is awake throughout.
  • Can you walk after a bone marrow transplant?
    Recovery after a bone marrow transplant is gradual but most patients can walk throughout the transplant period barring a few days time when they have low blood counts. It could take several weeks for the new bone marrow cells which were infused into the blood to travel to the bone marrow to begin to make healthy new cells. In some, it could take longer. This is why doctors will keep a steady watch on the recipients to monitor their progress. Depending on the type of transplant, and the risks of complications, doctors could recommend light forms of exercising like walking for short periods within the transplant unit itself.
  • How long is recovery after bone marrow transplant?
    Recovery after a bone marrow transplant is gradual. It takes up to 2 weeks for the newly infused cells to reach the bone marrow to begin to make healthy new cells. This process is called engraftment. In some recipients, it could take longer. During this time the immunity system can be weak. To prevent infections or the risk of complications, doctors recommend hospitalization for a few weeks to around 90 days to monitor the progress. Even after being discharged from the hospital, the bone marrow transplant recipients will have to visit the hospital for routine follow-ups with the doctors to check the response to the transplant.
Cancer Treatment At Fortis Hospital
With timely diagnosis, With Cancer, timely diagnosis can save your life. Fortis Hospitals has taken multiple safety measures so you receive safe care for all your health needs. With cancer detection and treatment, acting at the right time may make all the difference. So, don’t let the pandemic delay your cancer treatments, Visit Fortis Hospital, your Guardian of Health for Comprehensive and safe oncology and oncosurgery procedures.

Why Choose Us

  • 24*7 well equipped Ambulance and Emergency Services
  • More than 37 year of clinical experience
  • International Patients Services
  • Highly Advanced Medical Care
  • 24*7 well equipped Ambulance and Emergency Services
  • JCI and NABH Certified Hospital(Fortis Hospitals)
  • Dedicated Block for Oncology OPD’s

Our Team of Experts

Our patient’s stories

FAQs

  • What is the cut-off age (eligibility) for a bone marrow transplant?
    Bone marrow cell donors and recipients of all ages who meet strict health criteria are eligible for bone marrow transplant. This means both, the donor and the patient who is to receive the donor bone marrow cells, will undergo stringent tests to check for underlying risks and heath issues that could restrict the treatment. While younger donors under the age of 65 years are preferred for BMT, transplant recipients age can be extended upto 75 years if they are otherwise fit and without accompanying severe illness.
  • Can leukemia be cured after bone marrow transplant?
    There are four common types of leukemia. Of these, Acute Leukemia is the highly curable form of adult leukemia. This is attributed to the advances in the diagnosis and high-precision treatment of this type of blood cancer. Cure rates of 80-90 percent following bone marrow transplant have been reported from centers specializing in acute leukemia treatment, including Fortis Hospital in Mumbai, India.
  • Which family members can donate bone marrow?
    Seeking a bone marrow donor within the family is the first option. A brother or sister is most likely to be a perfect match as a donor. This is called a matched sibling donor transplant. There’s a 1 in 4 chance of the bone marrow cells matching among siblings. One’s parents, own children, and other relatives can sometimes be good matches. Only about 30% of those who need a bone marrow transplant can find a matching donor in their own family.
  • Is bone marrow transplant painful?
    The transplant procedure is not painful because it is not surgery. In fact, it is similar to a blood transfusion. The bone marrow cells are infused into the vein directly through a thin catheter or intravenous tube. This process could take a couple of hours and the recipient is awake throughout.
  • Can you walk after a bone marrow transplant?
    Recovery after a bone marrow transplant is gradual but most patients can walk throughout the transplant period barring a few days time when they have low blood counts. It could take several weeks for the new bone marrow cells which were infused into the blood to travel to the bone marrow to begin to make healthy new cells. In some, it could take longer. This is why doctors will keep a steady watch on the recipients to monitor their progress. Depending on the type of transplant, and the risks of complications, doctors could recommend light forms of exercising like walking for short periods within the transplant unit itself.
  • How long is recovery after bone marrow transplant?
    Recovery after a bone marrow transplant is gradual. It takes up to 2 weeks for the newly infused cells to reach the bone marrow to begin to make healthy new cells. This process is called engraftment. In some recipients, it could take longer. During this time the immunity system can be weak. To prevent infections or the risk of complications, doctors recommend hospitalization for a few weeks to around 90 days to monitor the progress. Even after being discharged from the hospital, the bone marrow transplant recipients will have to visit the hospital for routine follow-ups with the doctors to check the response to the transplant.
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